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KMID : 0848020030060030180
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Journal of Korean Breast Cancer Society
2003 Volume.6 No. 3 p.180 ~ p.185
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The Efficacy of Sentinel Node Biopsy Using Subareolar Injection of Radioactive Material in Breast Cancer
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김현아/Kim HA
이재혁/문병인/최금자/성순희/최혜영/서현숙/Lee JH/Moon BI/Choi KJ/Sung SH/Choi HY/Suh HS
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Abstract
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Purpose : This study was designed to evaluate the feasilbility of sentinel node biopsy (SNB) using subareolar injection of radioactive material in breast cancer.
Methods : The prospective study was performed of 112 breast cancers (T1 or T2 stages) at Ewha Womans University Mok-Dong Hospital from February 2001 to June 2003. Patients underwent lymphoscintigraphy using 99mTc sulfur colloid. The feasibility of SNB was assessed through comparison with simultaneous axillary node dissection.
Results : All patients were women, and the median age was 46 years. Internal mammary sentinel lymph node was identified in 2 cases (1.8%). The first node was appeared on lymphoscintigraphy around at 10.7 minutes after subareolar injection. Sentinel nodes could be identified in 111 (99.1%) among 112 patients with a gamma probe. The mean number of harvested sentinel nodes were 3.3 and metastasis was noted 80 of 368 nodes (21.7%). False negative rate was 4.1%.
Conclusion : SNB using subareolar injection of radioactive material could be a alternative method to replace axillary node dissection in T1 or T2 breast cancers, especially in case of clinical node negative patients.
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